Systematic survey reveals unannotated human gene that’s overexpressed in pituitary tumors

Credit: Frontiers of Medicine (2023). DOI: 10.1007/s11684-022-0968-4 A recent study focuses on the Ly-6 antigens, a family of proteins that contain a conserved LU domain. These antigens have been associated with stem cells and cancer stem cells. The mouse Ly-6A (also known as Sca-1) is a well-known marker for various stem cells, but its human homolog has been missing. Dan Liu and his team at Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong Read More

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